Follow these steps to create the Deep Hamburger Sausage & Pepperoni Pie:

1. Preheat Oven: Preheat your oven to 375°F (190°C).
2. Prepare Crust: Roll out the refrigerated pie crust and fit it into a deep-dish pie pan. Trim excess crust and set aside.
3. Cook Meat: In a large skillet over medium heat, cook the ground beef and Italian sausage until browned. Drain excess fat.
4. Add Vegetables: Stir in the diced onions and bell peppers. Cook until the veggies are softened, about 5 minutes.
5. Mix Ingredients: Add pepperoni, pizza sauce, Italian seasoning, garlic powder, salt, and pepper to the meat mixture. Stir until well combined.
6. Layer Cheese: Spread half of the shredded mozzarella and cheddar cheese on the bottom of the pie crust.
7. Fill Pie: Pour the meat and pepperoni mixture over the cheese layer, spreading it evenly.
8. Top with Cheese: Sprinkle the remaining mozzarella and cheddar cheese on top of the filling.
9. Cover with Crust: If desired, cut out a second circle of pie crust to place on top and cut slits for ventilation. If not, crimp the edges of the bottom crust to seal.
10. Apply Egg Wash: Beat the egg and brush it over the crust for a golden finish.
11. Bake: Place the pie in the preheated oven and bake for 45-50 minutes or until the crust is golden brown and the cheese is bubbly.
12. Cool: Let the pie cool for 10-15 minutes before slicing.

Following these instructions will help you create a delicious Deep Hamburger Sausage & Pepperoni Pie with minimal hassle.