Creating Nashville Hot Chicken Tenders is straightforward if you follow these simple steps:

1. Marinate the Chicken: In a bowl, combine buttermilk and hot sauce. Add the chicken tenders, ensuring they are well coated. Cover and refrigerate for at least 30 minutes.
2. Prepare the Coating: In another bowl, mix flour, cayenne pepper, paprika, garlic powder, onion powder, salt, and black pepper.
3. Heat the Oil: In a deep skillet or frying pan, heat oil over medium-high heat until it reaches 350°F (175°C).
4. Dredge the Chicken: Remove the chicken from the marinade. Dredge each tender in the flour mixture, pressing lightly to ensure an even coating.
5. Fry the Chicken: Carefully place the coated chicken tenders in the hot oil. Fry in batches to avoid overcrowding for about 5-7 minutes per side or until golden brown.
6. Drain the Chicken: Remove the tenders from the oil and place them on a wire rack or paper towel to drain excess oil.
7. Prepare the Spice Mixture: In a small bowl, combine melted butter and additional cayenne pepper for extra heat. Brush this mixture over the fried chicken tenders.
8. Serve: Optionally drizzle with more hot sauce to enhance the flavor.

These steps will guide you in creating these incredible Nashville Hot Chicken Tenders easily and effectively.